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HLH may refer to:

  • Hands Like Houses, an Australian rock band
  • Haydom Lutheran Hospital, in Manyara Region, Tanzania
  • Helix-loop-helix, a protein structural motif
  • Hemophagocytic lymphohistiocytosis, a blood disorder
  • Ulanhot Airport, in Inner Mongolia, China
  • High Level Hardware Limited, producers of the HLH Orion minicomputer