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Hippana or Hyppana ( Ancient Greek: ), was an ancient town of Sicily, mentioned by Polybius as being taken by assault by the Romans in the First Punic War, 260 BCE. (Pol. i. 24.) Diodorus, in relating the events of the same campaign, mentions the capture of a town called "Sittana", for which we should in all probability read "Hippana". (Diod. xxiii. 9.; Cluver.Sicil. p. 392.) The correctness of the name found in Polybius is confirmed by Stephanus of Byzantium (s. v.), who, however, writes it , but cites Polybius as his authority. It sat astride the main road from Panormus (modern Palermo) to Agrigentum (modern Agrigento) upon Monte dei Cavalli, in the modern comune of Prizzi.

Some manuscripts of Pliny mention the name of Ipanenses in his list of Sicilian towns. (iii. 8. s. 14. § 91), where the older editions have Ichanenses. If this reading be adopted, it in all probability refers to the same place as the Hippana of Polybius; but as the reading Ichanenses is also supported by the authority of Stephanus (who notices Ichana as a town of Sicily), the point must be considered doubtful.