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HI-SEAS (Hawaii Space Exploration Analog and Simulation) is an analog habitat for human spaceflight to Mars. HI-SEAS is located in an isolated position on the slopes of the Mauna Loa volcano on the island of Hawaii. The area has Mars-like features and an elevation of approximately 8,200 feet above sea level. HI-SEAS is funded by the NASA Human Research Program for four research missions. The missions are of extended duration from four months to a year.

The purpose of the detailed research studies is to determine what is required to keep a space flight crew happy and healthy during an extended mission to Mars and while living on Mars. Research into food, crew dynamics, behaviors, roles and performance, and other aspects of space flight and a mission on Mars itself is the primary focus. The HI-SEAS researchers also carry out studies on a variety of other topics as part of their daily activities.