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HEPACAM

Gene hepaCAM, named based on its original site of identification - hepatocytes and the nature of its protein product - a cell adhesion molecule (CAM), was first discovered and characterised in human liver and reported by Shali Shen (MD, PhD) in 2005. The gene encodes a protein of 416 amino acids, designated as hepaCAM, which is a new member of the immunoglobulin superfamily of cell adhesion molecules ( IgSF CAM). The main biological functions of hepaCAM include a) modulating cell adhesion and migration, and b) inhibiting cancer cell growth.