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HCW may refer to:

  • Cheraw Municipal Airport, in South Carolina, United States
  • Hartford College for Women, a former college affiliated with the University of Hartford
  • Health care worker
  • Holby City woman, a voter demographic in the 2010 United Kingdom general election
  • Horden Colliery Welfare A.F.C., an English football club
  • Hull–Chelsea–Wakefield Railway, in Quebec, Canada
  • Star1 Airlines, a Lithuanian airline