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Gurupá
''This article is about a city on the island of Marajó; for the island, see Ilha Grande do Gurupá; for the Amazon.com content delivery system, see Gurupa; for the Portuguese colonial land grant, see captaincy of Gurupá.

Gurupá or Santo Antonio de Gurupá is a municipality on the Amazon River in state of Pará, northern Brazil located near the world's largest river island, Marajó, 300 km upstream from the upper mouth of the river on the Atlantic coast.

The city is a center for palm heart extraction and commerce. It is a municipal seat and major river boat port.