Gubio is a Local Government Area of Borno State, Nigeria. Its headquarters are in the town of Gubio.
It has an area of 2,464 km² and a population of 152,778 at the 2006 census.
The postal code of the area is 602.
The primary road through Gubio runs north towards Damasak and south towards Maiduguri.
It is one of the sixteen LGAs that constitute the Borno Emirate, a traditional state located in Borno State, Nigeria.