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Guayas may refer to:

  • Ecuador:
    • Guayas River
    • Guayas Province
    • Guayas (ship)
    • Guayas (chief)
  • The fruit of the mamoncillo tree
Guayas (chief)

Guayas was a legendary chief of the Huancavilcas in the coastal plains of today Ecuador. The Huancavilcas lived in the area of today's Guayaquil at the time of the arrival of the Spanish.