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GSE may refer to:

  • Generic Stream Encapsulation, a link layer protocol for the Internet Protocol (IP)
  • Barcelona Graduate School of Economics (Barcelona GSE)
  • Guwahati Stock Exchange in Assam
  • GIAC Security Expert
  • Ghana Stock Exchange and its index, the GSE All-Share Index
  • General somatic efferent fibers of spinal nerve tracts
  • The IATA code for Gothenburg City Airport
  • Grapefruit seed extract
  • Gluten sensitive enteropathy
  • Great Soviet Encyclopedia
  • Georgian Soviet Encyclopedia
  • Green Street Elite, fictional football firm in the film Green Street
  • Golden State Exams, Californian State Exams
  • Government-sponsored enterprise, such as Fannie Mae and Freddie Mac
  • Ground support equipment, in the aviation industry
  • Group Study Exchange, a worldwide exchange program for young professionals of Rotary International
  • Gaussian Symplectic ensemble, used in Random matrix theory
  • GSE Systems, Inc.
  • Generic Substation Events
  • XNA Game Studio Express, Integrated Development Environment for creating computer games by Microsoft
  • Guvernanta Sonorilo Esperanto, the Esperanto Club at Norfolk Academy
  • Geocentric Solar Ecliptic System, a Cartesian coordinate system with center in the earth, X-axis pointing towards the sun and Z-axis parallel to the ecliptic pole