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GSC could refer to:

GSC (gene)

Homeobox protein goosecoid is a protein that in humans is encoded by the GSC gene. This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis.

Koller's sickle is the first to express the chick homeobox gene goosecoid (GSC).