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GLM may refer to:

  • Generalized linear model
  • General linear model
  • Generalized Lagrangian mean, a method in continuum mechanics to split a flow field into a mean (average) part and a wave part
  • Geostationary Lightning Mapper, an instrument being designed for the GOES-R series of satellites
  • Gilman (Amtrak station), Illinois, United States; Amtrak station code GLM
  • Global Language Monitor, media analytics organization
  • Groninger Luchtvaart Maatschappij, a Dutch airline
  • GlmY RNA or GlmZ RNA