Wikipedia
De Ghisolfi (also known as de Guizolfi, de Gisolfi, Guigursis, Guilgursis and Giexulfis) was the name of a Genoese- Jewish family prominent in the late Middle Ages and the early Renaissance.
In 1419, the Genoese Jew Simeone de Ghisolfi married a reigning princess of the municipality of Tmutarakan on the Taman Peninsula named Bikhakhanim, and took possession of this area, most likely centered on the town of Matrega. The de Ghisolfi clan ruled this principality as a protectorate of the Genoese consulate of Gazaria for much of the 15th century.
In 1453, the Republic of Genoa ceded its Crimean possessions to the Bank of St. George, a private enterprise to which it was heavily in debt. The Ghisolfi family continued to rule Matrega and the surrounding region on behalf of the Bank. Through such intermediaries as Khozi Kokos, they maintained relations with the rulers of Muscovy and other Russian principalities.