The Gartempe is a French river, 205 kilometres long. It is a left tributary of the Creuse River, which it joins in La Roche-Posay. Its source is in the municipality of Peyrabout.
Among its tributaries are the Anglin, the Brame and the Semme.
The Gartempe flows generally northwest, through the following departments and towns:
- Creuse: Peyrabout, Le Grand-Bourg
- Indre: Néons-sur-Creuse
- Indre-et-Loire: Yzeures-sur-Creuse
- Haute-Vienne: Châteauponsac, Rancon
- Vienne: Montmorillon, Saint-Savin, La Roche-Posay