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Florbetaben (18F)

Florbetaben, a fluorine-18 (18F)-labeled stilbene derivative (formerly known as BAY-949172), trade name NeuraCeq (florbetaben F18 injection), is a diagnostic radiopharmaceutical developed for routine clinical application to visualize ß-amyloid plaques in the brain. It is indicated for Positron Emission Tomography (PET) imaging of ß-amyloid neuritic plaque density in the brains of adult patients with cognitive impairment who are being evaluated for Alzheimer’s disease (AD) and other causes of cognitive impairment. The tracer successfully completed a global multicenter phase 0–III development program and obtained approval in Europe, US and South Korea in 2014.