Wiktionary
filaminast
n. A phosphodiesterase 4 inhibitor, used in the therapeutic treatment of asthma and chronic obstructive pulmonary disease.
Wikipedia
Filaminast
Filaminast (WAY-PDA 641) was a drug candidate developed by Wyeth-Ayerst. It was a phosphodiesterase 4 inhibitor ( PDE4 inhibitor) and an analog of rolipram, which served as a prototype molecule for several development efforts. It was discontinued after a Phase II trial showed that its therapeutic window was too narrow; it could not be dosed high enough without causing significant side effects (nausea and vomiting), which was a problem with the rolipram class of molecules.