Wikipedia
Estropipate
Estropipate ( INN, USAN, BAN) (brand names Harmogen, Improvera, Ogen, Ortho-Est, many others), also known as piperazine estrone sulfate, is a semi-synthetic, steroidal estrogen that is used mainly in hormone replacement therapy in the treatment of symptoms of menopause. It is a salt of estrone sulfate and piperazine, and is hydrolyzed into estrone in the body.