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ESCAPPM or ESCHAPPM is a mnemonic for the organisms with inducible beta-lactamase activity that is chromosomally mediated.

  • E: Enterobacter spp.
  • S: Serratia spp.
  • C: Citrobacter freundii
  • H: Hafnia spp.
  • A: Aeromonas spp.
  • P: Proteus spp. (P. vulgaris)
  • P: Providencia spp.
  • M: Morganella morganii

In vitro sensitivities are not applicable in vivo.

In general, treatment with cephalosporins results in inducible beta-lactamase activity. Treatment with an aminoglycoside or carbapenem is usually indicated. Carbapenems are a class of beta-lactam antibiotics with a broad spectrum of antibacterial activity. They have a structure that renders them highly resistant to beta-lactamases. Examples of Carbapenems include meropenem and imipenem.