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Epitranscriptomics

Epitranscriptomics describes an aspect of molecular genetics, or a study thereof, that depends on biochemical modifications of messenger RNA (mRNA) as well as other RNA biotypes. By analogy to the term epigenetics, described as "functionally relevant changes to the genome that do not involve a change in the nucleotide sequence", epitranscriptomics can be defined as a functionally relevant changes to the transcriptome that do not involve a change in the ribonucleotide sequence. The epitranscriptome, therefore, is defined as the ensemble of such functionally relevant changes. There are several types of RNA modification that impact on gene expression.