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Efes may refer to:

  • Efes, the Turkish name for the ancient Greek city of Ephesus
  • Efes Beverage Group, a Turkish beer company
  • Anadolu Efes S.K., a basketball club in İstanbul, Turkey sponsored by the above company
  • Efes Daromi, a Talmudic personality of the 3rd century
  • efes (אֶפֶס), the Hebrew word for zero