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EFB may refer to:

  • EfB Ishockey, a Danish professional Ice hockey team located in Esbjerg
  • Electronic flight bag, an electronic display system for flight crews
  • Esbjerg fB, a Danish football club
  • European Federation of Biotechnology, a non-profit association promoting Biotechnology
  • European foulbrood, a honeybee disease
  • French Bilingual School of South Carolina (École Française Bilingue - South Carolina)