What is "ebastine"

n. A particular antihistamine drug.

Ebastine (trade names Evastin, Kestine, Ebastel, Aleva, Ebatrol) is a H antihistamine with low potential for causing drowsiness.

It does not penetrate the blood–brain barrier to a significant amount and thus combines an effective block of the H receptor in peripheral tissue with a low incidence of central side effects, i.e. seldom causing sedation or drowsiness.

The patent in which the structure of ebastine is first mentioned is in Europe and in the US. The substance is often provided in micronised form due to poor water solubility.