Eastwick could refer to:
Eastwick was a fictional suburb on the outer reaches of the London Underground’s Metropolitan line in Julian Barnes’ novel Metroland. This book, written in 1980, recalled adolescence in the early 1960s.
Eastwick is a 2009 television series based on John Updike's novel The Witches of Eastwick. The series was developed by Maggie Friedman, and starred Paul Gross as the infamous Darryl Van Horne, alongside Jaime Ray Newman, Lindsay Price, and Rebecca Romijn as the eponymous witches.