What is "dysfibrinogenemia"

alt. (context medicine English) Any of a group of autosomal-dominant disorders of qualitatively abnormal fibrinogens. n. (context medicine English) Any of a group of autosomal-dominant disorders of qualitatively abnormal fibrinogens.

The dysfibrinogenemias are a group of autosomal dominant disorders of qualitatively abnormal fibrinogens. There are more than 350 different fibrinogen abnormalities, each named after the place where it was discovered. Each dysfibrinogenemia is associated with slightly different effects on the thrombin time and on normal clotting. Some dysfibrinogenemias cause abnormal bleeding or even thrombosis, while others have no effect on either bleeding or thrombosis.