DTK is an initialism that may refer to
- DTK (electronics), a digital unit that is connected between the engine's electronic controls and the fuel injection system.
- Datatech Systems Ltd., a company at the Toronto Stock Exchange
- Dietrich, AK, a location identifier
- Dry Dock Tackle Corp., a company
- Dunia Tanpa Koma, a TV series in Indonesia
- DTK Software, a company
- DTK Consulting Co., Ltd, an HR consulting company in Vietnam