DRQ may refer to:
- DRQ, a symbol seen on hardware schematics of computer systems with Direct memory access (DMA) functionality, means "DMA request"
- Dril-Quip, Inc., a company listed on the New York Stock Exchange as DRQ
- WDRQ, Detroit radio station marketed as "The new DRQ"
- DRQ, the main character in the critically acclaimed videogame GODS