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DPN may refer to:

  • Deaf President Now, a 1988 student protest at Gallaudet University to force the university to hire a deaf president
  • Democratic Party of Nauru, a political party in the Pacific nation of Nauru
  • Dermatosis papulosa nigra, a skin condition
  • Designated Portsmouth Number, a measure in the Portsmouth Yardstick system of handicapping for dissimilar boats in a race
  • Diphosphopyridine nucleotide, an old name for Nicotinamide adenine dinucleotide (NAD), a coenzyme found in all living cells
  • Dip-pen nanolithography, a scanning probe lithography technique
  • Doctorate of Philosophy in Nursing, a research degree similar to a Doctorate in Nursing Practice (DNP)
  • Double Pointed Needles, a type of knitting needle
  • Diseased Pariah News, a zine focusing on HIV and AIDS issues from the 1990s
  • Diffuse proliferative nephritis, a medical condition