What is "dotarizine"

n. A calcium channel blocker used in the treatment of migraine.

Dotarizine is a drug used in the treatment of migraine, which acts as a calcium channel blocker, and also as an antagonist at the 5HT receptor, and to a lesser extent at the 5HT and 5HT receptors. The anti-migraine action is thought to be due to its action as a vasodilator, but it also has some anxiolytic effects and blocks amnesia produced by electroconvulsive shock in animals.