What is "dopexamine"

n. A β1- and β2-adrenergic receptor agonist.

Dopexamine is a synthetic analogue of dopamine. Despite this, it is a β and β adrenoreceptor agonist. Its agonism of peripheral D dopamine receptors mediates relaxation of vascular smooth muscle in renal, mesenteric, cerebral and coronary arteries. Mild action at D receptors decreases norepinephrine (noradrenaline) release.

Use in sepsis has been proposed.

It is used as an inotropic agent in cardiac failure. Side effects include arrhythmia, tremor, angina and flushing.