The Collaborative International Dictionary
Disinure
Disinure \Dis`in*ure"\, v. t. [imp. & p. p. Disinured; p. pr. & vb. n. Disinuring.] [Pref. dis- + inure.] To render unaccustomed or unfamiliar.
We are hindered and disinured . . . towards the true
knowledge.
--Milton.
Wiktionary
disinure
vb. (context obsolete English) To make unfamiliar with something; to disaccustom.