DHR may stand for:
- Dlg homologous region in biochemistry;
- Digital Hardcore Recordings — a record label based in London;
- Darjeeling Himalayan Railway — a narrow gauge railway in India.
- Dhr.; 'De Heer, Dutch for mister
- Den Haan Rotterdam B.V., a Dutch manufacturer of nautical lanterns, searchlights and air horns
- Device History Record