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DFU may refer to:

  • Diabetic foot ulcer, a pathology that results directly from diabetes mellitus or long-term (or "chronic") complication of diabetes mellitus
  • Device Firmware Update, a capability of USB devices to update and backup firmware using a USB connection
  • Directions For Use, a document written for end-users of a product or device, often in the context of medical devices.
  • Dieter F. Uchtdorf (born 1940), German aviator, airline executive and religious leader
  • Dalian Fisheries University
  • Dansk Folkepartis Ungdom
  • Dartmouth Forensic Union
  • Dmitri Fedorovich Ustinov
  • Donald F. Ungurait
  • Dorados Fuerza UACH, a Mexican football club based in Chihuahua, Chihuahua, Mexico.The club represent the Autonomous University of Chihuahua. Currently playing in the Segunda División de México. The clubs makes its home in the Estadio Olímpico de la UACH
  • Dr. Farokh Udwadia
  • Dutch Fascist Union, a short-lived Fascist organization in the Netherlands. NFU emerged on February 26, 1933, following a split from the General Dutch Fascist League (ANFB). Leading figures were Karel Eduard van Charante and Tony W. Hooykaas
  • Den Frie Udstilling, a Danish artists association, founded in 1891 by artists in protest against the admission requirements for the Kunsthal Charlottenborg