Wiktionary
vb. (context transitive English) To make unfamiliar; to divest of familiarity.
Usage examples of "defamiliarize".
Instead of getting to know each other, becoming familiar with likes and dislikes, ticklish spots, pet peeves, Desdemona and Lefty tried to defamiliarize themselves with each other.
He needed to get this outside view to defamiliarize what he did, to see better what was going on.
He may imagine exotic foreign observers whose astonished reaction defamiliarizes the familiar and brings it under critical scrutiny.
Even now, time and this place still had their way of defamiliarizing the known and refamiliar-izing the unknown.
Paradoxically almost, the linguistic facility which makes Nabokov such an excellent game-player also encourages these readers, through its defamiliarizing effects, to think anew about artistry and reality, subjectivity and alterity, authority and autonomy.
Nabokov never allows the reader any sure grasp on the narrative, defamiliarizing or even snatching away a scene immediately upon describing it.