What is "decoglurant"

Decoglurant ( INN) (code name RG1578, RO4995819) is a negative allosteric modulator of the mGlu and mGlu receptors which was under development by Roche for the adjunctive treatment of major depressive disorder. Decoglurant progressed as far as phase II clinical trials but was ultimately discontinued from further development due to disappointing efficacy results.