What is "dabigatran"

n. (context medicine English) a direct thrombin inhibitor used as an oral anticoagulant for atrial fibrillation and other clinical conditions

Dabigatran (Pradaxa, Prazaxa) is an anticoagulant medication that can be taken by mouth. It is being studied for various uses and in some cases is an alternative to warfarin, since it does not have to be monitored by blood tests, but offers similar results in terms of efficacy.

In case of major bleeding, there is an antidote, idarucizumab (sold under the brand name Praxbind). A large study sponsored by the manufacturer found that idarucizumab effectively reversed anticoagulation by dabigatran within minutes.

It is in the class of a direct thrombin inhibitor. It was developed by the pharmaceutical company Boehringer Ingelheim.