Wiktionary
n. (context protein English) Any of a family of proteins that have a role in protein degradation and ubiquitinylation
Wikipedia
Cullins are a family of hydrophobic proteins providing a scaffold for ubiquitin ligases (E3). All eukaryotes appear to have cullins. They combine with RING proteins to form Cullin-RING ubiquitin ligases (CRLs) that are highly diverse and play a role in myriad cellular processes.
The human genome contains eight cullin genes
- CUL1, part of SCF complex
- CUL2, part of ECS complex ( Elongin C - CUL2 - SOCS-box)
- CUL3, part of CUL3-BTB complex
- CUL4A
- CUL4B
- CUL5
- CUL7
- CUL9, also known as PARC
There is also a more distant member called ANAPC2 (or APC2), part of the Anaphase-promoting complex.
CUL1, 2, 3, 4A, 4B, 5 and 7 each form part of a multi-subunit ubiquitin complex.
Usage examples of "cullin".
It would not be difficult—if Cullin would only wait another day until Company B came up.
Once there had been a time when he might have killed Cullin, when the memory of the vain sacrifice of the Fourth might have brought the hate surging red and unreasoning to his mind.
Knight sitting on the high stool, half turned away from the bar with his glass still in his hand and Cullin looming white-coated just within the doorway, alert and waiting for Knight to make a hostile move.
Nor would needling Cullin cause him to reveal the reasons for his presence in Punta Azul.
Carlos remained at the bar, following Cullin with the sights of his revolver.
Even Cullin, alone, could lift the ship by simple voice command to the drive control.
It was Cullin, wearing the black and gray uniform of a high official of the State Police, and he was alone.
You and I can now chat pleasantly about cabbages and kings and sealing wax and a man named Cullin who is, as you feared, going somewhere.
It was a command the robotic brain would obey instantly and Cullin could never countermand.
Vickson had paid the penalty and it had been gentle compared with the penalty Cullin would pay.
It would not be difficult—if Cullin would only wait another day until Company B came up.