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CSSD may refer to:

  • The Royal Central School of Speech and Drama, a drama school based in London
  • Central Sterile Services Department, an integrated place in hospitals and other health-care facilities that reprocesses sterilization and other actions on medical devices
  • Central Sterile Supply Department (in hospitals and clinics)
  • Cloneproof Schwartz Sequential Dropping, a single-winner election method
  • Computer Supported Spiritual Development, a field of study related to computer-supported collaboration
  • Czech Social Democratic Party