What is "cryoneuromodulation"

Cryoneuromodulation also known as cryoneurolysis, and commonly known in the media as Frotox or Notox, or by its trademarked name iovera°, was developed by myoscience Inc., a medical technology company based in Fremont, California. The iovera° system is a cryosurgical device for treating superficial and subcutaneous tissue structures.

The iovera° treatment, is indicated for the blocking of pain and additionally approved outside of the United States for the temporary treatment of wrinkles.