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Wiktionary
cross-breed
  1. Of or pertaining to the offspring produced by cross-breeding. alt. 1 To breed separate strains of the same species in order to create new traits. 2 To breed members of similar albeit distinct species, for example, horse X donkey = mule v

  2. 1 To breed separate strains of the same species in order to create new traits. 2 To breed members of similar albeit distinct species, for example, horse X donkey = mule

Usage examples of "cross-breed".

His craft is the breeding of animals, the way you must cross-breed or in-breed to get the best-yielding cows or the woolliest sheep.

Still, you're of good stock, and maybe cross-breeds are what's been lacking in our lines.

Their mission was to trade hides for food-plant seeds in the hope of cross-breeding hybrids which would grow very quickly during the ever-shortening northern summer.

Decide on some task, randomly cross-breed circuits that might or might not solve it, keep the ones that do better than the rest, and repeat for as many generations as it takes.

Instead of hunting down the heritable traits we needed in the wild, and struggling for years to produce cross-breeds bearing all of them, we designed every trait from scratch.