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CPX may refer to:

  • Benjamín Rivera Noriega Airport (IATA code), Puerto Rico
  • Dipropylcyclopentylxanthine, a drug
  • Clinical performance exam, formally objective structured clinical examination, a prerequisite to working in various health care fields
  • Clinopyroxene, monoclinic pyroxene, an igneous and metamorphic mineral
  • The Centre for Public Christianity (CPX) is a not-for-profit media company that offers a Christian perspective on contemporary life.