What is "corticoids"

Usage examples of "corticoids".

At least under stress the cholesterol content of the adrenal cortex falls, signifying that corticoids are being manufactured rapidly to meet the situation.

All the important corticoids have the same carbon skeleton, one differing from that of cholesterol chiefly in that the carbon chain attached to carbon-iy is reduced to 2 carbon atoms only, in place of cholesterol's 8.

Therefore the corticoids have 21 carbon atoms altogether instead of cholesterol's 27.

Since all the important corticoids possess a C=O group attached to carbon-3 (in place of the -OH group of cholesterol), all have this suffix.

There are other corticoids with effects similar to corticosterone, and of these the best-known is one which Kendall called "compound E" and Reichstein "substance Fa.

The corticoids have been divided into two groups: those which, like corticosterone and cortisone, possess an oxygen attached to carbon-n are the glycocorticoids and are concerned with glycogen storage.

The various corticoids, singly and together, could be used in cases of adrenal cortical failure much as insulin is used in diabetes.

However, after the isolation of the corticoids, their effects on various diseases of metabolism were inevitably studied.

Cortisone, like the other corticoids, has a particularly complex effect on the body, and there is always the danger of undesirable side effects.

To cite one case, a steroid that differs from the natural corticoids in possessing a fluorine atom attached to carbon-g is an unusually active glycocorticoid, ten times as active as the natural ones.

ACTH The production of corticoids is not controlled by direct feedback as insulin is by the blood glucose level it controls, or parathyroid hormone by the blood calcium level it controls.

The relationship between ACTH and the corticoids is analogous to that between TSH and the thyroid hormones.

Progesterone resembles the corticoids more than it does the estrogens.

Like the corticoids it has a 2-carbon chain attached to carbon-17, and it lacks the benzene ring of the estrogens.

The chief difference between progesterone and the corticoids is that the latter have a hydroxyl group on carbon-2i, whereas progesterone does not.