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COPP (chemotherapy)

COPP is a chemotherapy regimen for treatment of Hodgkin disease, consisting of concurrent treatment with (C)yclophosphamide, (O)ncovin, (P)rocarbazine and (P)rednisone.

It contains less procarbazine than MOPP (procarbazine is given only for 10 days in cycle instead of 14), and the very toxic mechlorethamine, which is prone to give severe neutropenia and to severely heighten the risk of secondary malignancies, is changed to less toxic cyclophosphamide, which is more safe to the progenitor stem cells (thus, less neutropenia) and less prone to give late secondary malignancies.

Thus, the COPP regimen is considered more safe and less toxic than MOPP. But it offsets with somewhat less efficacy, especially in advanced-stage Hodgkin disease.

Nevertheless, both the COPP and the MOPP are now supplanted by ABVD, which is less toxic and more effective than either COPP or MOPP.


Copp or Copps may refer to:

  • Doug Copp, promoter of the Triangle of Life, a technique he claims reduces casualties in earthquakes
  • Harold Copp, a Canadian scientist
  • Michael Copps (born 1940), on the Federal Communications Commission of the USA
  • Michael Copps Costello (1875–1936), Canadian politician
  • Sheila Copps (born 1952), Canadian politician
  • Stanley Copp (died 1987), Canadian politician
  • Terry Copp, Canadian military historian and Professor Emeritus
  • Victor Copps (1919–1988), Canadian politician
  • Certified Output Protection Protocol
  • Certificate of pharmaceutical product, a certificate which establishes the status of a pharmaceutical product
  • COPP (chemotherapy), a chemotherapy regimen for treatment of non-Hodgkin lymphoma
  • COPP ( Combined Operations Pilotage Parties), a defunct British special military unit
  • Copps Coliseum, a sports and entertainment venue in Hamilton, Ontario
  • Copps Food Center, a supermarket chain in Wisconsin