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Cofitachequi

Cofitachequi was a paramount chiefdom founded about 1300 AD and encountered by the Hernando de Soto expedition in South Carolina in April 1540. Cofitachequi was later visited by Juan Pardo during his two expeditions (1566–1568) and by Henry Woodward in 1670. Cofitachequi ceased to exist as a political entity prior to 1701.

The town and ceremonial center of Cofitachequi was located near the present-day city of Camden, South Carolina. Cofitachequi ruled a large number of towns in an area of several thousand square miles in the northeastern part of South Carolina. It was the easternmost extension of the Mississippian culture that extended over much of the southern part of the future United States.