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Wiktionary
close up shop

vb. (context idiomatic English) To stop what one is doing, especially the context of a business.

Usage examples of "close up shop".

The hours stated on the sign in his window were 10:00 to 10:00, but it was obvious to Doane by eight-thirty that he might as well close up shop.

If our street were anything like that book, I believe I would close up shop tomorrow!

Could he simply close up shop because he was irritated by a brief flurry of public exposure?

Do you think, Governor, it might be prudent for us just to close up shop until the world gets back to normal?