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CISS may refer to:

  • CISS-FM, Canadian radio station
  • Continuous Ink Supply System
  • Center for Intelligence and Security Studies, a center at the University of Mississippi
  • Concordia International School Shanghai,a coeducational day school Preschool to Grade 12 in Shanghai
  • Computed Images System & Services division, a 1960s division of General Electric, now called "Genigraphics"
  • Comité International des Sports des Sourds, "The International Committee of Sports for the Deaf"
  • Canadian International School System