CISL may mean:
- Confederazione Italiana Sindacati Lavoratori, the Italian Confederation of Workers' Trade Unions
- Continental Indoor Soccer League. An Indoor Soccer League 1993-1997
- CISL (AM), a radio station in Richmond, British Columbia.
- Computational and Information Systems Laboratory, a division of NCAR
CISL is a Canadian radio station, in Vancouver, British Columbia, owned by Newcap Radio. The station currently offers an easy listening/ adult standards format branded as "CISL 650 Smooth & Easy" broadcasting at 650 AM. It is one of Canada's few remaining successful music stations on the AM dial. The calls in its moniker are generally pronounced "C-Isle".
CISL's studios are located in Richmond, while its transmitters are located on Lulu Island.