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Wiktionary
chloramphenicol

n. (context medicine English) A broad-spectrum antibiotic originally derived from the bacterium ''Streptomyces venezuelae'' but now produced synthetically

WordNet
chloramphenicol

n. an oral antibiotic (trade name Chloromycetin) used to treat serious infections (especially typhoid fever) [syn: Chloromycetin]

Wikipedia
Chloramphenicol

Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes meningitis, plague, cholera, and typhoid fever. Its use is only recommended when safer antibiotics cannot be used. Monitoring both blood levels of the medication and blood cell levels every two days is recommended during treatment. It is available intravenously, by mouth, and as an eye ointment.

Common side effects include bone marrow suppression, nausea, and diarrhea. The bone marrow suppression may result in death. To reduce the risk of side effects treatment duration should be as short as possible. People with liver or kidney problems may need lower doses. In young children a condition known as gray baby syndrome may occur which results in a swollen stomach and low blood pressure. Its use near the end of pregnancy and during breastfeeding is typically not recommended. Chloramphenicol is a broad-spectrum antibiotic that typically stops bacterial growth by stopping the production of proteins.

Chloramphenicol was discovered in 1947. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is available as a generic medication. The wholesale cost in the developing world of an intravenous dose is about 0.40 to 1.90 USD. In the United States it is very expensive. Global issues relating to bacterial resistance have revived interest in its use.

Usage examples of "chloramphenicol".

The chloramphenicol will be long out of his system, and his doctors will not know about his previous bout of aplastic anemia.

And Streptomyces bacteria produce a host of antibiotics, including streptomycin, tetracycline, neomycin, chloramphenicol, and erythromycin.

To fight her infection, she was given a succession of antibiotics: ampicillin, chloramphenicol, gentamicin, nafcillin, ceftriaxone, clindamycin, tobramycin, and ceftazidime.

In South Africa a strain was found to be resistant not only to penicillin, but to most of its successors, including ampicillin, streptomycin, methicillin, chloramphenicol, and tetracycline.

To fight her infection, she was given a succession of antibiotics: ampicillin, chloramphenicol, gentamicin, nafcillin, ceftriaxone, clindamycin, tobramycin, and ceftazidime.

Without some kind of stainless steel no sulfa drugs for infections, no DDT, no chloramphenicol to cure diseases like typhoid and typhus.

All in favor of my proposal to send our existing stock of chloramphenicol and most of our sulfa drugs to Luebeck and Amsterdam, along with as much DDT as we can manage, raise your hands.

In addition, to prepare for the more difficult process of making chloramphenicol, our chemists are producing small quantities of an antibiotic called sulfanilamide, which can be used to prevent wound infections.

Senate committee investigation concluded that the bacteria had mutated into a superbug because the drug industry had aggressively promoted chloramphenicol for a wide variety of infections in Mexico and other developing countries.

There was a companyI can't remember the name, this was back in the early eightiesit started marketing an antidiarrhea drug containing chloramphenicol and tetracycline in the form of a chocolate flavored pill.

Once it was clear that Sunny's botulinum was multiresistantneither chloramphenicol nor metronidazole appeared to have any impactPatou was brought into the case, as a matter of course.

He was also given heavy doses of antibiotics, including a gram of chloramphenicol, a gram of oxacillin, two million units of penicillin.