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CHCA may refer to:

  • CHCA-TV, a defunct television station (channel 6) licensed to Red Deer, Alberta, Canada
  • Child Health Corporation of America, a business alliance of child-care hospitals, headquartered in Shawnee Mission, Kansas
  • The Collier Heights Community Association (CHCA), a community association in Atlanta, Georgia, USA
  • The Colorado Hill Climb Association, the group which organizes and supports motorized hill-climbing races in Colorado, USA
  • Community Health Charities of America, a non-profit organization headquartered in Arlington, Virginia, USA
  • Cincinnati Hills Christian Academy, a private university preparatory school in Cincinnati, Ohio, USA
  • α-Cyano-4-hydroxycinnamic acid, a phenylpropanoid used as a matrix for peptides and nucleotides in matrix-assisted laser desorption/ionization mass spectrometry analyses