Crossword clues for chaperone
chaperone
Longman Dictionary of Contemporary English
Wiktionary
n. 1 An older person who accompanies other younger people to ensure the propriety of their behaviour, often an older woman accompanying a young woman. 2 (context biology English) A protein that assists the non-covalent folding/unfolding and the assembly/disassembly of other macromolecular structures, but does not occur in these structures when the latter are performing their normal biological functions. vb. to act as a chaperone
WordNet
Wikipedia
In molecular biology, molecular chaperones are proteins that assist the covalent folding or unfolding and the assembly or disassembly of other macromolecular structures. Chaperones are present when the macromolecules perform their normal biological functions and have correctly completed the processes of folding and/or assembly. The chaperones are concerned primarily with protein folding. The first protein to be called a chaperone assists the assembly of nucleosomes from folded histones and DNA and such assembly chaperones, especially in the nucleus, are concerned with the assembly of folded subunits into oligomeric structures.
One major function of chaperones is to prevent both newly synthesised polypeptide chains and assembled subunits from aggregating into nonfunctional structures. It is for this reason that many chaperones, but by no means all, are heat shock proteins because the tendency to aggregate increases as proteins are denatured by stress. In this case, chaperones do not convey any additional steric information required for proteins to fold. However, some highly specific 'steric chaperones' do convey unique structural (steric) information onto proteins, which cannot be folded spontaneously. Such proteins violate Anfinsen's dogma, requiring protein dynamics to fold correctly.
Various approaches have been applied to study the structure, dynamics and functioning of chaperones. Bulk biochemical measurements have informed us on the protein folding efficiency, and prevention of aggregation when chaperones are present during protein folding. Recent advances in single-molecule analysis have brought insights into structural heterogeneity of chaperones, folding intermediates and affinity of chaperones for unstructured and structured protein chains.
A chaperone (more often spelled chaperon) in its original social usage was a person who for propriety's sake accompanied an unmarried girl in public: usually she was an older married woman, and most commonly the girl's own mother.
In modern social usage a chaperon (frequent in British spelling) or chaperone (usual in American spelling) is a responsible adult who accompanies and supervises young people. By extension, the word chaperone is used in clinical contexts.
Chaperone or Chaperon may refer to:
- Chaperone (social) or chaperon, a person who accompanies or supervises young people on social occasions
- Chaperone (clinical), a person who acts as a witness for a patient and a medical practitioner during a medical examination or procedure
- Chaperon (headgear), a form of hood or versatile hat worn in Western Europe in the Middle Ages
In clinical medicine, a chaperone is a person who serves as a witness for both a patient and a medical practitioner as a safeguard for both parties during a medical examination or procedure. The exact responsibilities vary according to the clinical situation.
Chaperones are widely used for gynecological and other intimate examinations. A chaperone may support the patient with reassurance and emotional support during a procedure or examination that the patient may find embarrassing or uncomfortable. The chaperone may also provide practical help to the doctor during an examination or procedure. In other clinical settings the chaperone could protect the doctor from physical attack.
As a witness, the chaperone can help the doctor disprove unfounded allegations having been present during a procedure and witnessed continuing consent.
Category:Healthcare occupations
Usage examples of "chaperone".
Best we can tell, the original vector technology, as used by Grace, included some other exotic moleculethe French have named it Chaperone, because that is what Benoit Moreau called it.
Reluctantly she permitted Dolley to join with other young people, chaperoned of course, in attending parties, picnics, jaunts into the country.
Botticelli for me and the fattest whore in Florence, with plenty left over for her elephant of a mother to act as chaperone!
So, with Caspar to chaperone them, they had crossed the streets of Haarlem at dusk.
You are not my chaperone and I am not some thirteen-year-old waiting for the chance to sneak off for a roll in the haymow with the boy from two farms over.
Large arrays of cylindrical structures and their chaperoning conduits and connectors were at once majestic yet stylized in design.
And so, for one reason and another, they walked on in silence, chaperoned by the voice of Mrs.
She was forever being chaperoned about by her mother or some other elderly female relative, which was all very well for a new debutante but decidedly slow for a lady of twenty three.
The Dowager Countess was chaperoning her daughter to the ball and was keeping a closer eye on her than she had done at Lady Phillips's.
She will be well enough chaperoned by her rector and his wife until her auntie arrives.
I don't suddenly discover that I have been chaperoning a set of German code-dispatches across the seas.
I would have to do the chaperoning for her, and she did hope that I would not forget what I was sent for, or get talking with somebody, and leave Miss Gage altogether to Kendricks.
And this was very observable in the case of the girls, who were chaperoning their mothers-- shrinking women who seemed a little confused by the bustle, and a little awed by the machinery of the great caravansary.
To send them in one direction and the party chaperoned in another is certainly original.
Cortlandt was chaperoning, who behaved with an elaboration of restraint and propriety that kept Irene in a flutter of uneasiness.