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CDH may refer to:

  • Central DuPage Hospital, Illinois, U.S.A.
  • Centre Démocrate Humaniste, a Belgian political party
  • Cloudera's Distribution including Apache Hadoop
  • The Computational Diffie-Hellman assumption, that a certain mathematical problem is hard
  • Congenital diaphragmatic hernia
  • Cretin-Derham Hall, school in St. Paul, Minnesota, U.S.A.
  • Cellobiose dehydrogenase, a plant enzyme