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CBZ (or cbz) may refer to:

  • Cedric Bixler-Zavala, singer for At the Drive-In, The Mars Volta, Zavalaz, Antemasque
  • Carbamazepine, an anticonvulsant and mood stabilizing drug
  • Carboxybenzyl, a common amine protecting group in organic synthesis
  • C-B-Z red vine cuvée (Cabernet Sauvignon, Blauburger, Zweigelt). NB: 'Blauburgunder' is also the German name for Pinot Noir.
  • CBZ-FM, a CBC Radio 2 station in Fredericton, Canada
    • CBZF-FM, a CBC Radio 1 station in Fredericton which had the call sign CBZ until 2004.
  • CBZ Holdings, a financial services company of Zimbabwe
  • .cbz, a file extension for the Comic Book Archive file format
  • Hero Honda CBZ, a 4-stroke sports oriented bike by Hero Honda Motors India Ltd